Oikos K, at the western wing of the Asklepieion, housed the cult of Artemis, after the abandonment of the temple of Orthia. The Oikos is rectangular, and divided into three aisles with two colonnades. At the back was a pedestal with a marble cult statue of the goddess. It was carved by the sculptor Damophon and depicted the goddess wearing a short chiton (tunic) and a fawnskin, and holding a torch. In front of the statue stood an offering table and around it pedestals of statues of priestesses and young girls in initiation.

Fragments of the statues are exhibited in the Archaeological Museum of ancient Messene. Artemis was worshiped in the city as Orthia, as Phosphoros (the light bearer), as well as Oupesia (the one who stands over and helps women in childbirth). She was associated with the upbringing of young girls and their transition from childhood to marriageable age.